Ajai Chari Selected Research

ON123300

3/2016

Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.

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Ajai Chari Research Topics

Disease

93	Multiple Myeloma 02/2022 - 09/2010
18	Neoplasms (Cancer) 01/2022 - 01/2013
5	Infections 02/2022 - 01/2017
5	COVID-19 01/2021 - 01/2020
4	Disease Progression 11/2021 - 05/2015
3	Fatigue 12/2021 - 04/2016
3	Smoldering Multiple Myeloma 01/2021 - 01/2018
3	Agammaglobulinemia (Hypogammaglobulinemia) 01/2021 - 01/2020
3	Hypertension (High Blood Pressure) 11/2020 - 10/2018
3	Neutropenia 01/2020 - 01/2017
3	Hematologic Neoplasms (Hematological Malignancy) 01/2018 - 07/2010
2	Nausea 12/2021 - 01/2020
2	Thrombocytopenia (Thrombopenia) 12/2021 - 01/2020
2	Exanthema (Rash) 01/2018 - 11/2016
2	Lymphoma (Lymphomas) 01/2016 - 12/2009
2	Leukemia 01/2016 - 12/2014
2	Plasma Cell Neoplasms 10/2013 - 10/2012
1	Body Weight (Weight, Body) 11/2022
1	Cytokine Release Syndrome 09/2021
1	Cytopenia 09/2021
1	Bone Diseases (Bone Disease) 12/2020
1	Melanoma (Melanoma, Malignant) 02/2020
1	Frailty 01/2020
1	Diarrhea 01/2020
1	Hyponatremia 01/2020
1	Vomiting 01/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Chalazion 05/2019
1	Blepharitis 05/2019
1	Myopia 03/2019

Drug/Important Bio-Agent (IBA)

24	daratumumabIBA 01/2022 - 01/2016
24	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 11/2016
15	Proteasome InhibitorsIBA 11/2021 - 09/2010
14	selinexorIBA 01/2022 - 01/2018
14	Bortezomib (Velcade)FDA Link 01/2022 - 09/2010
13	carfilzomibIBA 12/2021 - 12/2014
12	Monoclonal AntibodiesIBA 09/2021 - 04/2016
11	Lenalidomide (CC 5013)FDA Link 01/2022 - 01/2016
8	Pharmaceutical PreparationsIBA 10/2021 - 09/2010
7	Immunomodulating AgentsIBA 11/2021 - 04/2016
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2016
4	Immunoglobulins (Immunoglobulin)IBA 02/2022 - 10/2012
4	B-Cell Maturation AntigenIBA 09/2021 - 01/2020
4	ixazomibIBA 09/2021 - 09/2016
3	PanobinostatIBA 11/2021 - 09/2018
3	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 09/2021 - 01/2020
3	Exportin 1 ProteinIBA 01/2021 - 01/2018
3	Melphalan (Alkeran)FDA LinkGeneric 11/2020 - 03/2016
3	AntigensIBA 02/2020 - 01/2017
2	filanesibIBA 01/2022 - 11/2016
2	KinesinsIBA 01/2022 - 11/2016
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2020
2	belantamab mafodotinIBA 11/2021 - 01/2020
2	Immunoconjugates (Immunoconjugate)IBA 12/2020 - 01/2020
2	Immunoglobulin G (IgG)IBA 11/2020 - 06/2020
2	ibrutinibIBA 08/2020 - 11/2018
2	Ferritins (Ferritin)IBA 06/2020 - 01/2020
2	fibrin fragment D (D-dimer)IBA 06/2020 - 01/2020
2	pomalidomideIBA 01/2020 - 01/2017
2	Biological ProductsIBA 12/2014 - 12/2014
2	ParaproteinsIBA 10/2013 - 12/2009
1	Etoposide (VP 16)FDA LinkGeneric 01/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	InterferonsIBA 01/2022
1	7- chloro- 8- hydroxy- 1- (3'- iodophenyl)- 3- methyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepine (TISCH)IBA 12/2021
1	Histone Deacetylase InhibitorsIBA 11/2021
1	SteroidsIBA 10/2021
1	Bispecific AntibodiesIBA 09/2021
1	Immunologic Factors (Immunomodulators)IBA 09/2021
1	insulin receptor-related receptor (IRR)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	isatuximabIBA 01/2021
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021
1	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 01/2021
1	Neurokinin-1 Receptor AntagonistsIBA 01/2020
1	bismuth subsalicylate (Pepto-bismol)FDA LinkGeneric 01/2020
1	Olanzapine (Zyprexa)FDA Link 01/2020
1	Protein Subunit VaccinesIBA 01/2020
1	CannabinoidsIBA 01/2020
1	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 01/2020
1	Loperamide (Imodium)FDA LinkGeneric 01/2020
1	MegestrolIBA 01/2020
1	Methylphenidate (Ritalin)FDA LinkGeneric 01/2020
1	SodiumIBA 01/2020
1	VaccinesIBA 01/2020
1	Thrombopoietin ReceptorsIBA 01/2020
1	Serotonin 5-HT3 Receptor AntagonistsIBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019

Therapy/Procedure

37	Therapeutics 02/2022 - 01/2013
3	Stem Cell Transplantation 10/2020 - 09/2015
3	Immunotherapy 01/2020 - 01/2016
3	Transplantation 01/2018 - 07/2010
2	Drug Therapy (Chemotherapy) 01/2022 - 06/2015
2	Artificial Respiration (Mechanical Ventilation) 11/2020 - 06/2020
2	Platelet Transfusion (Blood Platelet Transfusions) 01/2020 - 01/2018
1	Subcutaneous Injections 11/2022
1	Radiotherapy 01/2022
1	Intravenous Infusions 01/2020
1	Injections 11/2019
1	Lenses 03/2019